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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fb45a2e0c849ff48632b6747d5d37de6c37dda6d79db7d786398ec48bc2a3746' 
  AND token = 'NLMvCubqNUsXvyRdwVpt+z9RrY2F6rDkn3pXuHvwEPc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}