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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '189924f8a89a91a1002d4914fc067b69e97786f0698748987272285b2600954c' 
  AND token = 'PUl64vcIZ6u295U/18YcjenVfixR2azXUuOMH21qoRU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}