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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8127e204c3e7f8a28d74cb6834a56aff7f726319b728b91bb80ecda40c8dd77a' 
  AND token = '9wJBIGsU1M65gragC9vurTKNuu6iLWaOpjRr8iGIFEM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}