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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9046b4b4251ec525cd54a1eb46f1305c6132d8a2429287eb35a8f021b56af1a8' 
  AND token = 'hJ7ie6PSqwP13GmoApWr21ILBew6AGB4OyWvwxPTIuM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}