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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33a86d95e742c00222bba8b363df84341bab1353d86c24454134e6acf1a0cd4c' 
  AND token = 'EYESdP/QfCU3Gsm2uAYp0n5PZB+M3g50v8Vbhi6RGPs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}