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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d21409b76179480e89f9197f996c8068d501b71e2f77d5e9129c8835c92fb18' 
  AND token = 'DG7j7r5NAxwYH1fSKBwYXuos740+quz3eD+Z2PJNm74=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}