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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a8e20abd49ac15df856c53252d1115c5c5623d6e1739b20bd4272214b6e4a71c' 
  AND token = 'T/IO703C4wdYmO7jAXXVwoUrP/C4iLhEOP9V4o6SNqY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}