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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '106069f7a95ff23d2105c3ddaaa64ae55158dbd8bf6442f3153bee16752800bc' 
  AND token = '+HF0FaRrLgIZ3idvr+mmyy5D+t7K7s0uiYDOGd9HVcI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}