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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2855e1583d334c6b75fd708a078e1418be70f8177a5f7a1d8f01e5e442ca5a28' 
  AND token = 'hLZCkHGx1B3yx2rDXa9NXts1a7uBaD5wiUSsqmlNSos=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}