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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f5ec2b01b12cb1be714b4af2e22e5c866a5a039e9d1014c795aa004302bb3fd' 
  AND token = 'W/rva1AxQwdeAiisB+LCaumivnhYCJBQkpf5zxjKVz0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}