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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '109c40040a7b0e7d945adc2e422ca6e3a6b6ce58f1b8a0a247eb529d97249e8c' 
  AND token = 'e6uT0p0NeG/xmKm3tHdiIP0eeWotz+N1J7YEmD0LM2U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}