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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c889466aa8375f77088e2708fbc721e7e7ccbbd3b09304fafa38a4ed19b4ec0e' 
  AND token = 'HFUxZlPj33GRhXNX5PTMk2qjwBAkJ6S6ktlZnFBxwo4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}