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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44660b220c065a1262fa30a37dd0a1959febb98b0338bec7b0a0953bf077c452' 
  AND token = 'tP7IE59nyiM70/tBaurQkOr+8smiJ07v5x+gcb/ARTc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}