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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a14c82d7a830b284c3e450e43c53112c2700252025905f573d858b0d0fcdadd' 
  AND token = 'B21RnIZO/aDl+6NDT7qA1jdUySdLoXagIfjK7zJ9j9Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}