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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b65057655f161fca04069319ed31a510f27ecf6b0eb24377d092002c3717c860' 
  AND token = 'xv67vMWc6r/Tc6bcAnM8tHKdCgkw8E6CWMaJvOtZSEM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}