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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b827054f75d08ae7fc4b643eaae9f9e02dd795a04d98d48388d2522892c3290' 
  AND token = 'U5FRp2XH/RwXYC9/jur1XCOEemvDVLGg5TbXHELOEDw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}