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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2c8b9e1676cfb23d2b7d1d47de0745e7b5a18c80a0ed6f836243581f980933f' 
  AND token = 'wxrWAyg1+A8lpve70cfZ9Fdbv35r1oaeXlQfp9M/z4Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}