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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c8745a7bebb2fa60bef90797767f24da981f1d926f9315afed67b36205b43856' 
  AND token = 'x5gDuAzO00N1r10zQoUz53HnolQr6bRwYdD5KcZS+wM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}