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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '042c9f239e74504608440dafb0039fe2091a0daa64e32dcb3eb3997c215c2bc8' 
  AND token = 'fDwWhAaFjuOwgCSUoIwZAsFszsXIt63Wl7DTRjOC0cE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}