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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c065abb48dcdff6c84fa880d112d529db4ec0e09700ec1ba08ae80828acc1272' 
  AND token = 'qISw5dZhgkwnF0xOB74x+h0tVuKbUABtED+hPKpm71Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}