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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16d4be6a7b1c260182e9a7cfc368f94cc51c76191021c0f3b4155a1450668a53' 
  AND token = 'jDYxm3Ca8bUdAQYFCMaANza2nQtzxWhwtHesZNEZjYM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}