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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '688c3649ea2ff64d2983d847f35b6699be62d7fd98810c01be620685d8bcb411' 
  AND token = 'E1JV3MWf6fVBImRElZq/+S+8EMWkPAuqRsK+IXSyGaU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}