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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74ba121cb79139c29e7a3cecf0500c1974107cbe9f2b3545fcffbd23c396f133' 
  AND token = 'ghsWBVP7E2bsaU50RnmfEwnENC+qtD1Hhb87bn8lynE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}