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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '849cfb1d56549ca78922c6dd6f8d1fe7d2ef424ccc40f20ac5b0fc05318a228f' 
  AND token = 'hAknPmoE1e+2w2PDslzVE2eiJ4TSPhOrU65bbve4XSw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}