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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b1f50ad3ad29aad2a734ac66a8d8edb644eacf2cae928642f01a50ae443ca493' 
  AND token = 'oCOv80TBwLQw2PB7mWhtQZRmdZIete+tAWcFf2v0wJA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}