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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b3381a2afef5bfed9e5787f6de551dce1a45ea1b3a9d9dcfe985d438f6f3eda' 
  AND token = '61YOYwPVyhQWChwfPR7Fn1+oG10VTRpKagkcFJH0JEM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}