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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f7eb5c838f881d7ad081a2f3b5a4c6ffe9535e02f5837b792d3c41037f9e63d9' 
  AND token = 'bYyw4w06emosMH5rL+5Y4aSlEoQqYTfGDNrXu4Y37F0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}