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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd601d9836d842a86fefdf54c10dc7ec64b13653001511ea1a5e5ff651fb6cd3f' 
  AND token = 'IjEzhC7e7OJNG5L4GxwBT15Mx9tSaZhBdRhYUZg90KQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}