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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '778a6a21b7a53140b782e9267cd109e3bf61eaaa3662cf770d52de54a2c1f790' 
  AND token = 'raxG+WIblo5iPICEH3qiXJHz+aJ0UYUcqKFsxlO9dGo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}