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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a5bc9240ffb810dc64892fe6c62ecb81f322200298d8ab3fb39491929d56e11' 
  AND token = 'Ozu++E6Jo2fZgccYw6To8FRzz6+HAcHiQjp9d0n2Zqw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}