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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '423fbb4c898521bf005802e038c07287e6df06aebd100a2334b1eb7ed6005e24' 
  AND token = 'cQ3GV/jlUicL+D/py8QTkpiIlnDfLiZc0m0vDOunmcU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}