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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f53c113f76d214825574bd898561018a6e73dc85f0e0e56d2d433335b2e2e494' 
  AND token = 'aRpWg1Wp3fydCheBzyweL4QA9qobuwVfhjNx389GV78=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}