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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18a321b98c52a2d95eefc6acc8b292841dc02a9efb54400dbac5b00085cac5b8' 
  AND token = 'FXOaNnnZxcI/eREanxS6ByeinW4aYk1Wdlmo6KJsZcA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00053

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}