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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4326de1dcccf9c2ce396366d69c45d1cd5be25a813ae123ee20dc229cf795410' 
  AND token = 'rI/JqugFbjbBSoAtOQhDB/gQaZYjhn1T22NsLFQNCHY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}