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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '943cd6a07b9327e4d484b32da41b8aa71c1816bf6beba18e334610044a61fa5f' 
  AND token = '4e1FgdNtSRRFARKBSYmczUX7C3+UIA4hTls+VNfWNn4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}