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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '004c35720740b373a63965dbe0480576ffb884db2a2934b9fbdc8d8350bc1afa' 
  AND token = 'LT+S/pixc5BPqVyUbkdSUrppdn6WSGG+/qT0Jy90WUY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}