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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d3b3b9cef45d008dd888327a1d38b1928f9537d3c7f9934b906c010d3da78d8' 
  AND token = '59bNckevarNmXgL7UuwFuaoqwg3ZpBRmWc7DvzlzRZI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}