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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a0dfde6f965a97c7116dab221bca54e3ba85dfc063995e41b41a965c066ea5c' 
  AND token = 'QXiQh+5UM0+grgc8hEje/QdZ48D3uEIDZPBvAPa8png=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}