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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd43b3a698bd3194dadb56e4a143a25cdebbbbf34e7e441327839575bc7ef60b4' 
  AND token = 'TkUKX1blilU5o2s8fzVsp7SC2cX9sYEKtKMugxZpq8M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}