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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '643b301619f034e140ac3fee00127fb6019f417a6a03800dc2797a4cf534ee2e' 
  AND token = 'K7yN2uRd0Ei7/p6nfRd52Mt7c6da8IcWuTv+GIPUXfs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}