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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00221ea08f4505a8eff563722bc0b5cd31c24486d286809fb5ad873863a9eb90' 
  AND token = 'fj4Eems4brai6pSuK/XXpILiwmvIxTFKQNLSZjt62N8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}