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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '291210e3fe34b94fce1a3312a63b80952e63baf1d0e76cd25af6601ad7906055' 
  AND token = '2Ji/d3Ps6Sb+CZQubBLpXqGn7cRQbvbhpEF3MwUSZEg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}