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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e1aea0d38abffbeb36f5f2fe2593c7dc74017a6707cfcb4374ea254ee716e9b' 
  AND token = 'ZPXPI5ApVNXtzfrvH4eLZOvQ/j32f0h6Ql2/CLro1Do=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}