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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53466b0128bdac65d3431f36e45c38bdc18087c37ed2baf1f3e9a34c3f49c566' 
  AND token = '9IYLUcswEg2u8fQJM+ZNRpiaU7t+Fu2MOxNl3LRqRKs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}