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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fbbbe17e2ceff307cc9ef16a8848c33a30280be61cdf3665049265398fc04921' 
  AND token = 'qZCbNl+EqLmjfKDKgmgXE4UI2XqD1RSASq5OIYMS7d0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}