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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7187632eed34c749ee635e1c0a151690e4f66516b3a9eacdbcf77e236e001f32' 
  AND token = 'vGraguRBAGXRPf67u/5czKTe757Ka88yJtr6dhtIICw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}