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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6bd37fd1d807135400b1485c07278b6a70f38385cc651498d25c2b77d280c134' 
  AND token = 'bkqf7TOZV1b9WwTyDD23OHgxDKay518j10zpDy2jvJ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}