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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a335530dc9c2f4b44a69619b2826b69bb4b764171df618deef9ef945cfb44aab' 
  AND token = 'mQ1i/Gegk0hH3DrYkU9w0lGhK4acTYW8eiYsvskof68=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}