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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4891e0b4b740d5ee156519f96ff143faf6a5930d199f2e30cc1c8df011f1cd9b' 
  AND token = '3gAQD4hYbmjVMCsaLGVrZzHCpEu7dT0R6pEqvYkioKc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}