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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '653bafe080c55565253164fa801c562898f05eebd8189ea10417a7b747ec0860' 
  AND token = 'xWtw5g1I2OgJanK7Ga4/Lwd8FOumqsDOmr3NP3lExtg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}